Table 4.
Results of the mediation analyses of LPCB body burden and depressive symptoms through HVA/crea using MEDIATE macro for SPSS [30]; controlled for age, albumin and traumatic experience
| Coefficient | SE | t | p | |
|---|---|---|---|---|
| Total effect model (DV = depressive symptoms_t2) | ||||
| LPCBs | .48 | .24 | 2.05 | .02 |
| Covariates | ||||
| Age | −.05 | .04 | −1.17 | .12 |
| Albumin | −.12 | .19 | −0.60 | .28 |
| Traumatic experience | 1.62 | 1.37 | 1.18 | .12 |
| Depressive symptoms_t1 | .75 | .09 | 8.60 | <.001 |
| Model fit | ||||
| R2 | .62 | <.001 | ||
| F | 26.67 | |||
| Effect of IV on HVA (mediator) | ||||
| LPCBs | −.75 | .50 | −1.50 | .07 |
| Effect of IV and mediator on depressive symptoms_t2 | ||||
| HVA/crea | −.13 | .05 | −2.61 | .01 |
| LPCBs | .38 | .23 | 1.67 | <.05 |
| Model fit | ||||
| R2 | .65 | <.001 | ||
| F | 24.92 | |||
| Homogeneity of regression (LPCB*HVA) | ||||
| R2 | .0004 | .38 | ||
| F | 0.10 | |||
Note: DV dependent variable, IV independent variable, t1 measurement occasion 1, t2 measurement occasion 2, LPCBs lower-chlorinated biphenyls, HVA homovanillic acid / creatinine, R 2 explained variance, F F-value, SE standard error, t t-value, p p-value (significance)