Table 5.
Results of the mediation analyses of HPCB body burden and depressive symptoms through HVA/crea using MEDIATE macro for SPSS [30]; controlled for age, albumin and traumatic experience
| Coefficient | SE | t | p | |
|---|---|---|---|---|
| Total effect model (DV = depressive symptoms_t2) | ||||
| HPCBs | .94 | .39 | 2.40 | .01 |
| Covariates | ||||
| Age | −.08 | .04 | −1.96 | .03 |
| Albumin | −.14 | .19 | −.72 | .27 |
| Traumatic experience | 1.61 | 1.36 | 1.19 | .12 |
| Depressive symptoms_t1 | .75 | .09 | 8.79 | <.001 |
| Model fit | ||||
| R2 | .62 | <.001 | ||
| F | 27.45 | |||
| Effect of IV on HVA (mediator) | ||||
| HPCBs | −1.84 | .82 | −2.24 | .02 |
| Effect of IV and mediator on depressive symptoms_t2 | ||||
| HVA/crea | −.12 | .05 | −2.40 | .01 |
| HPCBs | .71 | .39 | 1.82 | .04 |
| Model fit | ||||
| R2 | .65 | <.001 | ||
| F | 25.17 | |||
| Homogeneity of regression (HPCB*HVA) | ||||
| R2 | .002 | .25 | ||
| F | 0.47 | |||
Note: DV dependent variable, IV independent variable, t1 measurement occasion 1, t2 measurement occasion 2, HPCBs higher-chlorinated biphenyls, HVA homovanillic acid/creatinine, R 2 explained variance, F F-value, SE standard error, t t-value, p p-value (significance)