Table 2.
Parameters | ||||
---|---|---|---|---|
| ||||
Treatment | AUC0–8h (nmol/L* h) | Cmax (nmol/L) | Tmax (h) | |
Mv-3-glucoside | ZDF-CNTL | N.D. | N.D. | N.D. |
LN-CNTL | N.D. | N.D. | N.D. | |
ZDF-SGP | 2.31 ± 0.53 | 0.90 ± 0.28 | 0.83 ± 0.58 | |
LN-SGP | 2.66 ± 0.50 | 1.04 ± 0.20 | 0.25 ± 0.00 | |
| ||||
Pt-glucoside | ZDF-CNTL | N.D. | N.D. | N.D. |
LN-CNTL | N.D. | N.D. | N.D. | |
ZDF-SGP | 1.59 ± 0.13 | 0.62 ± 0.09 | 0.83 ± 0.58 | |
LN-SGP | 1.90 ± 0.33 | 0.74 ± 0.08 | 0.25 ± 0.00 | |
| ||||
Dp-glucoside | ZDF-CNTL | N.D. | N.D. | N.D. |
LN-CNTL | N.D. | N.D. | N.D. | |
ZDF-SGP | 2.13 ± 0.39 | 1.26 ± 0.48 | 0.75 ± 0.25 | |
LN-SGP | 2.58 ± 0.29 | 1.72 ± 0.24 | 0.75 ± 0.25 | |
| ||||
Pn-glucoside | ZDF-CNTL | N.D. | N.D. | N.D. |
LN-CNTL | N.D. | N.D. | N.D. | |
ZDF-SGP | 2.38 ± 0.63 | 0.81 ± 0.27 | 0.25 ± 0.00 | |
LN-SGP | 2.75 ± 0.55 | 0.97 ± 0.19 | 0.25 ± 0.00 | |
| ||||
Cy-3-glucoside | ZDF-CNTL | N.D. | N.D. | N.D. |
LN-CNTL | N.D. | N.D. | N.D. | |
ZDF-SGP | 1.91 ± 0.53 | 1.18 ± 0.45 | 0.83 ± 0.58 | |
LN-SGP | 2.23 ± 0.49 | 1.50 ± 0.28 | 0.25 ± 0.00 |
Significant difference from ZDF-SGP and LN-SGP groups. p < 0.05
ZDF = Zucker diabetic fatty rat
LN =Zucker lean rat
CNTL = control