Table 7.
Characteristics for subgroups of FCCTX [15].
Majority (Membranous beta-catenin, 61%) | Minority (Nuclear beta-catenin, 39%) | P-value |
---|---|---|
Younger age of onset of CRC (53.7 years) | Older age of onset of CRC (58.6 years) | Not given |
Dominance of right-sided CRC | Dominance of left-sided CRC | Not given |
Microsatellite- and chromosomal stable (MSS/CIN-) | Microsatellite stable and chromosomal unstable (MSS/CIN+) | 0.005 |
Infrequent p53 mutations | p53 mutations (p = 0.011) are associated with various 18q losses | Not given |