Table 5.

Host – pathogen interactions revealed from the text mining of the literature.

S. No	Host Pathogen Interactions		Interactions Causes	Reference
	Pathogen Proteins	Human Proteins
1	CagA	E-cadherin	Gastric cancer	Murata-Kamiya et al. [48]
		Erk mitogen-activated protein kinase	Gastric cancer	Zhu et al. [47]
		Transforming growth factor-b-activated kinase 1 (TAK1)	Gastric cancer	Lamb et al. [46]
		Src family kinases	Gastric cancer	Higashi et al. [49]
		human kinase PAR1b/MARK2	Gastric cancer	Nesić et al. [45]
2	CagE type IV secretion system	Dendritic cells	MALT and Gastric cancer	Donald et al. [50]
		NF- B activator. TAK1, TRAF6, and MyD88	Intestinal metaplasia and Gastric cancer	Hirata et al. [51]
3	Holliday junctions resolves	Mus81	block DNA replication	Chen et al. [52]
4	Mechanosensitive ion channel protein	integrin-b-catenin	human articular chondrocyte (HAC) responses	Lee et al. [53]
		Focal Adhesion Kinase pp125FAK	osteoblast activation	Rezzonico et al. [54]
5	Type IV secretion system	protein kinase B, PKB	Gastric cancer	King et al. [55]
6	GTPase	Guanine Nucleotide Exchange FactorSec7 Domain	IL-8 expression	Mossessova et al. [56]
7	Transpoase	RNA-proteins	To regulate the RNA-proteins network	Kelley et al. [57]
8	VacA	VIP54	Infection/Gastric cancer	de Bernard et al. [44]