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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 Oct;2(7):566–574. doi: 10.1016/j.bpsc.2017.04.006

Figure 2. Effects of Lamotrigine and Ketamine on Prefrontal Functional Connectivity.

Figure 2

(A) Voxel-wise paired t-tests with family-wise-error correction revealed significant reductions of GBCr 2h post lamotrigine (blue) and (B) increased GBCr during ketamine infusion (red). The color bar depicts the z values of reduced (blue) and increased (yellow-red) GBCr. The black line delineates the prefrontal cortex region. Abbreviations: GBCr = Global Brain Connectivity with global signal regression;