Table 3.

Mortality rates and hazard ratios for amlodipine vs. chlorthalidone and lisinopril vs. chlorthalidone treatment groups for cases with either baseline or in-trial atrial fibrillation/flutter

Mortality	Chlorthalidone (n=383)	Amlodipine (n=247)					Lisinopril (n=224)
			Unadjusted		Adjusted			Unadjusted		Adjusted
	n, 10-yr Rate/100 Persons	n, 10-yr Rate/100 Persons	HR (95% CI)	P	HR (95% CI)	P	n, 10-yr Rate/100 Persons	HR (95% CI)	P	HR (95% CI)	P
All-cause*	236 67.91	115 49.45	0.67(0.54,0.83)	<0.001	0.68(0.54,0.87)	0.002	129 66.04	0.84(0.68,1.04)	0.108	0.83(0.66,1.05)	0.123
CVD	132 44.77	70 32.49	0.73(0.55,0.97)	0.030	0.78(0.57,1.06)	0.113	70 41.92	0.81(0.60,1.08)	0.146	0.81(0.59,1.11)	0.184
Non-CVD	96 37.46	40 18.94	0.58(0.41,0.83)	0.003	0.55(0.37,0.83)	0.004	53 36.43	0.86(0.62,1.20)	0.375	0.83(0.58,1.19)	0.316

Abbreviations: CI, confidence interval; CVD, cardiovascular disease; HR, hazard ratio; yr, year.

^*All-cause includes CVD, non-CVD, and unknown.