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There are no stable interactions between the C2A and C2B domains of Syt7 in solution. Superpositions of 1H-15N HSQC spectra of the Syt7 C2AB fragment (black contours), the Syt7 C2A domain (green contours) or C2B domain (red contours) in the presence of 1 mM EDTA (A) or 2 mM Ca2+ (B).
