Figure 4.

Paeonol inhibits MPP+-induced increase of caspase-1, COX2, and iNOS at protein level in astrocytes. Compared with the control group, there were higher protein levels of caspase-1 (A, B), COX2 (A, C), and iNOS (A, D) in astrocytes treated by MPP+, which were repressed by paeonol (0.75, 1, 1.5 μmol/L). ^## p<0.01 indicates there was a significant difference between the control group and PD group, * p<0.05 or ** p<0.01 indicates there was a significant difference between the PD group and PD+Paeonol groups.