Table 4. Expression of SLAMF4 on peripheral blood T and B lymphocytes, monocytes and on T cell differentiated subsets on healthy donors and patients with SLE.
| SLAMF4 | |||||
|---|---|---|---|---|---|
| Healthy Donors (n = 12–22) | SLE patients (n = 14–25) | p valueb | |||
| Mean (%)a | SEM | Mean (%) | SEM | ||
| CD4 | 5.0 | 1.4 | 3.6 | 1.9 | 0.925 |
| CD8 | 56.4 | 2.6 | 45.1 | 3.7 | 0.025 |
| DNT | 77.2 | 4.3 | 55.7 | 5.0 | 0.0000020 |
| B cells | 0.6 | 0.1 | 0.2 | 0.1 | 0.944 |
| Monocytes | 99.0 | 0.3 | 95.3 | 2.2 | 0.856 |
| CD4+ T cells | |||||
| Naïve | 1.1 | 0.4 | 0.9 | 0.3 | 1.000 |
| CM | 1.3 | 0.3 | 1.2 | 0.4 | 1.000 |
| EM | 11.7 | 2.4 | 5.0 | 1.6 | 0.232 |
| CD8+ T cells | |||||
| Naïve | 2.5 | 0.9 | 2.3 | 0.8 | 1.000 |
| CM | 48.4 | 3.9 | 37.8 | 4.4 | 0.014 |
| EM | 85.8 | 2.4 | 75.7 | 4.4 | 0.020 |
| TDEM | 93.2 | 1.7 | 88.6 | 2.6 | 0.563 |
a Results are expressed as mean percentage (%) ± SEM.
b p values ≤ 0.05 are considered statistically significant