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. 2017 Oct 11;12(10):e0185786. doi: 10.1371/journal.pone.0185786

Fig 7. Macrophages depletion reduces LLC tumour growth in DUSP3-/- mice.

Fig 7

Tumours were established by i.v. injection of 106 LLC-Luc+ cells to clodronate-liposomes-depleted mice. (A) Representative xenogen imaging results and (B) quantification of the xenogen bioluminescence imaging data shown in A at day 14 after LLC injection. (C) Comparison of lung weights. (D) Representative hematoxylin eosin staining of lung sections from DUSP3+/+ and DUSP3-/- mice injected with PBS-lipsomes or clodronate-liposomes. (E) Comparison of tumour areas from each group. Student-t-test was used for statistical analysis. *p < 0.05, **p < 0.01 and ***p < 0.001. 3 mice were used in each group and for each experiment. Data shown are representative of 3 different experiments.