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. 2017 Oct 11;12(10):e0186222. doi: 10.1371/journal.pone.0186222

Table 4. Comparison of adiponectin, leptin and L/A in the diagnosis of MS.

AUC P NRI (%) P IDI (%) P Variables used for comparison
Boys
Leptin (ng/ml) 0.798
Adiponectin (ug/ml) 0.697 < 0.001 -28.65 < 0.001 -5.30 < 0.001 Leptin
L/A (ng/ug) 0.822 0.001 13.15 0.010 2.92 0.001 Leptin
< 0.001 39.49 < 0.001 8.22 < 0.001 Adiponectin
Girls
Leptin (ng/ml) 0.773
Adiponectin (ug/ml) 0.689 0.001 -15.89 0.022 -3.10 0.003 Leptin
L/A (ng/ug) 0.793 0.019 42.72 < 0.001 1.92 0.031 Leptin
< 0.001 19.20 0.001 1.18 0.100 Adiponectin

Abbreviation: L/A: leptin to adiponectin ratio; MS: metabolic syndrome; AUC: area under the curve; NRI: net reclassification improvement; IDI: integrated discrimination index.

The original values of leptin, adiponectin and L/A were used to calculate the AUCs, NRI and IDI.