Fig 1. Inter-chromosomal epistasis between chromosomes 5 and 6 regulates fasting plasma glucose levels in mice.

Plasma glucose levels were measured in 5-week-old (A) female and (B) male mice that were fasted overnight. Each dot represents the glucose level of a single mouse. “Others” represents the data from all mice in this study excluding the other 4 strains shown in that panel. The black horizontal line indicates the mean glucose level for each group. The red horizontal line indicates the predicted trait level based on a model of additivity.