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. 2017 Oct 11;3(10):eaao1874. doi: 10.1126/sciadv.aao1874

Fig. 2. β diversity of gut communities from mice born vaginally or by C-section during early development.

Fig. 2

(A) Principal coordinate analysis (PCoA) of the fecal microbiota by birth mode at all time points. Communities segregate significantly by birth mode (P = 0.001). PC, principal coordinate. (B) PCoA of fecal microbiota of mice born vaginally or by C-section (by age). Differences in fecal microbiota were significant during early development, from weaning to week 6 (P = 0.001). (C) Microbiome maturity indices calculated by a random forest model trained on microbial communities from vaginally delivered mice. (D) Unweighted UniFrac distances of fecal communities at any age from 6 weeks of age of vaginally born mice. Distances are highest at weaning and at 6 weeks of age. For (A) and (B), significance was determined pairwise by ANOSIM test, with resampling 999 times. For (D), significance was determined pairwise by ANOVA test, with resampling 999 times.