Skip to main content
. 2017 Mar;17(1):255–261. doi: 10.4314/ahs.v17i1.31

Table 2.

Physcian's pattern of hydroxyurea prescription

Variables Frequency(n) Percentage (%)
Starting dose (mg/kg/day)
Less than 10mg/kg 15 62.5
10 – 20 mg/kg 9 37.5
>20mg/kg - -
Mean(SD)=10.61(3.31), Median=9.01, Min=7.35, Max=17.24
Current dose (mg/kg/day)*
Less than 10mg/kg 5 25.0
10 – 20 mg/kg 15 75.0
>20mg/kg - -
Mean(SD)= 13.49(3.73), Median=15.05, Min=7.81, Max=17.86
Indications for commencement of
hydroxyurea**
Frequent/Severe VOC 19 79.2
Moderate Disease 3 12.5
High leucocyte/platelet
Counts
1 4.2
Severe symptomatic
anaemia
1 4.2
Severe/Recurrent ACS 1 4.2
Indications for discontinuation of hydroxyurea
Conception/Fertility 3 12.5
Unbearable Reactions 1 4.2

N=24(40% of all subjects),

*

20 subjects on current use,

**

multiple responses