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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Am J Surg Pathol. 2017 Nov;41(11):1491–1498. doi: 10.1097/PAS.0000000000000939

Table 4.

Relationship between Grades of Acute and Chronic Inflammation or Eosinophilic Inflammation and Chronic Architectural and Non-architectural Changes*

Grades of Acute and Chronic Inflammation

Chronic Architectural and Non-architectural Changes Total I/II III IV/V p-values

Surface villiform Changes (n) 366 38 237 91
  Present 136 3 (2%) 86 (63%) 47 (35%) <0.0001
  Absent 230 35 (15%) 151 (66%) 44 (19%)

Basal Plasmacytosis (n) 338 37 217 84
  Present 178 7 (4%) 115 (65%) 56 (31%) <0.0001
  Absent 160 30 (19%) 102 (64%) 28 (18%)

Basal lymphoid Aggregates (n) 338 37 217 84
  Present 214 9 (4%) 141 (66%) 64 (30%) <0.0001
  Absent 124 28 (23%) 76 (61%) 20 (16%)

Paneth cell metaplasia (n) 369 39 238 92
  Present 30 4 (13%) 14 (47%) 12 (40%) 0.09
  Absent 339 35 (10%) 224 (66%) 80 (24%)

Eosinophilic Inflammation

Total Grade 1 Grades 2, 3, or 4 p-value

Surface villiform Changes (n) 366 154 212
  Present 136 47 (35%) 89 (65%) 0.03
  Absent 230 107 (47%) 123 (53%)

Basal Plasmacytosis (n) 338 137 201
  Present 178 59 (33%) 119 (67%) 0.004
  Absent 160 78 (49%) 82 (51%)

Basal lymphoid Aggregates (n) 338 137 201
  Present 214 71 (33%) 143 (67%) 0.0003
  Absent 124 66 (53%) 58 (47%)

Paneth cell metaplasia (n) 360 155 214
  Present 30 10 (33%) 20 (67%) 0.43
  Absent 339 145 (43%) 194 (57%)
*

counts and percentages in ()