TABLE 1.
Summary of the thermodynamic data of HMBPP binding to BTN3A1 domains derived from ITC measurements in different conditions
| BTN3A1 domain | ΔH (kJ/mol) | TΔS (kJ/mol) | Kd (μM) | n |
|---|---|---|---|---|
| BFI | −53.7 | −21.6 | 2.36 | 0.845 |
| BFI+diphosphate | −32.9 | −1.1 | 2.61 | 0.860 |
| B30.2 | −53.7 | −23.0 | 4.27 | 0.994 |
| B30.2+diphosphate | −38.4 | −7.7 | 4.10 | 1.070 |