FIG. 5. Intracellular signals of RON activation for the growth and invasion in gastric cancer cells. CDKI: Cycline-dependent kinase inhibitor, CDK4: Cycline-dependent kinase 4, MAPK: Mitogen-activated protein kinases, Erk1/2: extracellular signal-regulated kinase 1/2, JNK: c-Jun N-terminal kinases, AP-1: Activator protein-1, NF-kB: nuclear factor kappa-light-chain-enhancer of activated B cells, UPAR: Urokinase receptor.
