Fig. 5.

BMP signaling regulates mitochondrial β-oxidation to control lipid metabolism. a Metabolic gene expression profiles between wild type and the BMP/sma mutants. b Mitochondrial β-oxidation genes are induced in the sma mutants. Error bars represent s.d., ***P < 0.001, Student’s t-test (unpaired, two-tailed), N = 3. c The loss-of-function mutant of acs-2(ok2457) significantly increases the lipid content level of the sma-3 mutant. Error bars represent standard error (s.e.), ***P < 0.001, Student’s t-test (unpaired, two-tailed), n = 87 for WT, n = 74 for acs-2, n = 57 for sma-3, n = 63 for acs-2;sma-3. d acs-2 inactivation does not suppress the decrease in body size of the sma-3 mutant. Error bars represent s.e., n.s. P > 0.05, Student’s t-test (unpaired, two-tailed), n = 39 for WT, n = 29 for acs-2, n = 34 for sma-3, and n = 29 for sma-3;acs-2