Table 2.
Baseline characteristics comparing patients with early (0–30 days) versus late (> 30 days) resumption of antithrombotic therapy (early, n = 100 versus late, n = 201), 6 missing because of incomplete data
| Early resumption ( N = 100) | Late resumption ( N = 202) | P -value | |
|---|---|---|---|
| Age, years ± SD | 78.1 (9.4) | 78.6 (9.4) | 0.70 |
| Female, n (%) | 28 (28.0) | 59 (29.2) | 0.83 |
| Charlson comorbidity index >1, n (%) | 55 (55.0) | 93 (46.0) | 0.14 |
| Level of independence | 0.85 | ||
| Independent, n (%) | 69 (70.4) | 137 (67.8) | |
| Homecare/nursing home, n (%) | 29 (29.6) | 65 (32.2) | |
| Missing, n = 2 | |||
| Glasgow Coma Scale (GCS), n (%) | 0.42 | ||
| GCS 3–8 | 6 (6.2) | 6 (3.0) | |
| GCS 9–12 | 9 (9.3) | 17 (8.6) | |
| GCS 13–15 | 82 (84.5) | 175 (88.4) | |
| Missing, n = 7 | |||
| Hematoma density, n (%) | 0.18 | ||
| Hypodense | 29 (30.2) | 40 (20.2) | |
| Mixed density | 40 (41.7) | 106 (53.5) | |
| Isodense | 24 (25.0) | 48 (24.2) | |
| Hyperdense | 3 (3.1) | 4 (2.0) | |
| Missing, n = 8 | |||
| Midline shift, mm ± SD | 7.5 (4.2) | 7.6 (4.4) | 0.94 |
| Missing, n = 7 | |||
| Platelet inhibitor, n (%) | 62 (62.0) | 131 (64.9) | 0.63 |
| Aspirin | 59 (59.0) | 124 (61.4) | |
| Clopidogrel | 4 (4.0) | 8 (4.0) | |
| Dipyridamole | 7 (7.0) | 8 (4.0) | |
| Anticoagulant, n (%) | 40 (40.0) | 73 (36.1) | 0.51 |
| Warfarin | 37 (37.0) | 72 (35.6) | |
| LMWH | 3 (3.0) | 1 (0.5) | |
| Combined platelet inhibitor + anticoagulant, n (%) | 2 (2.0) | 2 (1.0) | 0.47 |
| Main indication(s) of AT therapy, n (%) | |||
| 28 (28.0) | 52 (25.9) | 0.69 | |
| TIA/stroke | 27 (27.0) | 46 (22.8) | 0.42 |
| Coronary heart disease | 8 (8.0) | 9 (4.5) | 0.21 |
| Mechanical valve | 6 (6.0) | 11 (5.4) | 0.84 |
| Peripheral vascular disease | 40 (40.0) | 86 (42.8) | 0.64 |
| Atrial fibrillation | 3 (3.0) | 4 (2.0) | 0.58 |
| Venous thromboembolism | 22 (22.0) | 32 (15.8) | 0.20 |
| Multiple indications | |||
| Reversal of AT effect, n (%) | 37 (37.0) | 77 (38.1) | 0.85 |
| Bridging AT therapy, n (%) | 23 (23.0) | 32 (15.8) | 0.13 |
| Last INR > 1.5 preop, n (%) | 2 (2.1) | 7 (3.7) | 0.46 |
| Missing, n = 14 | |||
| General anesthesia, n (%) | 3 (3.0) | 5 (2.5) | 0.79 |
| Bilateral surgery, n (%) | 15 (15.5) | 34 (17.2) | 0.71 |
| Missing, n = 7 |
Abbreviations: LMWH = low molecular weight heparin, TIA = transient ischemic attack