Figure 1. The mRNA expression of (A) PPAR-γ, (B) COX-2, (C) IL-6, and (D) TNF-α in granulosa cells from stimulated follicles in polycystic ovary syndrome (PCOS) and non-PCOS women. The mRNA copy number is given to allow comparison. PPAR-γ and COX-2 mRNA was significantly downregulated in the granulosa cells of PCOS women compared with controls (p=0.034 and p=0.018, respectively), but IL-6 and TNF-α mRNA did not show significant differences. PPAR, peroxisome proliferator-activated receptor; COX, cyclooxygenase; IL, interleukin; TNF, tumor necrosis factor. a)p<0.01.
