Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A schematic diagram of the mechanism by which M19 inhibits osteoclast differentiation. RANKL-RANK signaling induces NFATc1 expression through NF-κB, MAPKs and PI3K/Akt pathways. M19 acts on the RPS5 and blocks NF-κB, MAPKs and PI3K/Akt pathways and, subsequently, suppresses NFATc1 expression
