Table 1. Univariate and multivariate analysis of OS in different Cezanne expressions of HCC patients.
| Variables |
Low Cezanne expression |
High Cezanne expression |
||||||
|---|---|---|---|---|---|---|---|---|
| Univariate |
Multivariate |
Univariate |
Multivariate |
|||||
| P-value | P-value | HR | 95% CI | P-value | P-value | HR | 95% CI | |
| Gender (female versus male) | NS | NS | NS | NS | ||||
| Age, years (⩽50 versus >50) | NS | NS | NS | NS | ||||
| AFP (ng/ml) (⩽400 versus >400) | NS | NS | NS | NS | ||||
| HBsAg (negative versus positive) | NS | NS | 0.001 | 0.003 | 0.307 | 0.143–0.662 | ||
| GGT (U/l) (⩽50 versus >50) | NS | NS | <0.001 | NS | ||||
| Liver cirrhosis (no versus yes) | <0.001 | 0.001 | 2.504 | 1.465–4.282 | NS | NS | ||
| Tumor size (cm) (⩽5 versus >5) | 0.014 | 0.001 | 1.928 | 1.310–2.836 | <0.001 | 0.021 | 1.976 | 1.108–3.525 |
| Tumor number (single versus multiple) | NS | NS | <0.001 | 0.026 | 1.894 | 1.077–3.328 | ||
| Satellite nodule (no versus yes) | NS | NS | NS | NS | ||||
| Tumor capsule (no/ incomplete versus complete) | NS | NS | NS | NS | ||||
| Tumor differentiation (I–II versus III–IV) | NS | NS | NS | NS | ||||
| Vascular invasion (no versus yes) | NS | NS | 0.009 | NS | ||||
| Adjuvant TACE (no versus yes) | 0.002 | 0.002 | 0.536 | 0.362–0.794 | 0.038 | NS | ||
Abbreviations: AFP, α-fetoprotein; CI, confidential interval; GGT, γ-glutamyltransferase; HR, hazard ratio; NS, not significant; OS, overall survival; TACE, transcatheter arterial chemoembolization