Table 2. Univariate and multivariate analysis of TTR in different Cezanne expressions of HCC patients.
| Variables |
Low Cezanne expression |
High Cezanne expression |
||||||
|---|---|---|---|---|---|---|---|---|
| Univariate |
Multivariate |
Univariate |
Multivariate |
|||||
| P-value | P-value | HR | 95% CI | P-value | P-value | HR | 95% CI | |
| Gender (female versus male) | NS | NS | NS | NS | ||||
| Age, years (⩽50 versus >50) | NS | NS | NS | NS | ||||
| AFP (ng/ml) (⩽400 versus >400) | NS | NS | 0.050 | NS | ||||
| HBsAg (negative versus positive) | 0.018 | NS | 0.007 | 0.019 | 0.445 | 0.226–0.874 | ||
| GGT (U/l) (⩽50 versus >50) | NS | NS | <0.001 | NS | ||||
| Liver cirrhosis (no versus yes) | 0.001 | 0.018 | 1.767 | 1.104–2.828 | NS | NS | ||
| Tumor size (cm) (⩽5 versus >5) | 0.023 | 0.001 | 1.843 | 1.298–2.617 | <0.001 | 0.005 | 2.218 | 1.265–3.899 |
| Tumor number (single versus multiple) | NS | NS | <0.001 | 0.023 | 2.025 | 1.103–3.718 | ||
| Satellite nodule (no versus yes) | NS | NS | 0.003 | NS | ||||
| Tumor capsule (no/ incomplete versus complete) | NS | NS | NS | NS | ||||
| Tumor differentiation (I–II versus III–IV) | NS | NS | NS | NS | ||||
| Vascular invasion (no versus yes) | NS | NS | 0.002 | NS | ||||
| Adjuvant TACE (no versus yes) | 0.002 | 0.002 | 0.568 | 0.397–0.812 | <0.001 | NS | ||
Abbreviations: AFP, α-fetoprotein; CI, confidential interval; GGT, γ-glutamyltransferase; HR, hazard ratio; NS, not significant; TACE, transcatheter arterial chemoembolization; TTR, time to recurrence