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. 2017 Sep 7;8(9):e3035. doi: 10.1038/cddis.2017.433

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Copyright © 2017 The Author(s)

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Bioinformatics analysis of proteins identified from MALDI-IMS. (a) Schematic illustration of the workflow of bioinformatics analyses. (b) Total PPI network was established for the five proteins identified from MALDI-IMS. (c) Sub-PPI network for LRP6-related proteins was extracted from the total network. (d) Predicted LRP6-related proteins were divided into several groups based on their function. (e) Predicted LRP6-related proteins involved in the regulation of cell proliferation