Table 3.
Prevalence of single nucleotide polymorphism (−443) in the promoter region of osteopontin gene and allelle frequency in patients and control
| SNP at nt − 443 |
Genotypes | Allelle frequency | |||||
| C/C | C/T | T/T | P-value | C | T | P-value | |
| Patients | 8 (9.2%) | 35(40.2%) | 44 (50.6%) | 51 (29.3%) | 123 (70.7%) | ||
| Control | 4 (16%) | 13 (52%) | 8 (32%) | 0.22* | 21(42%) | 29 (58%) | 0.2 |
| Responders | 4 (8.0%) | 20 (40%) | 26(52%) | 28 (28%) | 72 (72%) | ||
| Non responders |
4 (10.8%) | 16 (43.25%) | 17 (45.95%) | 0.65* | 36 (48.65%) | 38 (51.35%) | 0.7 |
*
The comparison was made between TT genotype against C/T+C/C assuming a dominant model