Fig. 3. (a) Quartz-crystal microbalance with dissipation (QCM-D experiments) monitoring of non-binding substrate (duplicate experiments 2 and 3). Experiment 1 data (in green) correspond to the blank experiment. Dissipation vs. normalized frequency plots at different times are displayed. Starting times correspond to the bottom-left corner of graph. (b) Cartoon representing the behavior of a non-binding oligodeoxynucleotide. (c) QCM-D scans showing the behavior of a GpG-containing oligodeoxynucleotide (duplicate experiments 4 and 5). (d) Cartoon representing specific binding between 1a and immobilized oligodeoxynucleotides.
