Fig. 4.
Neuroanatomical associations of auditory task performance in the patient cohort. The Figure shows statistical parametric maps (SPMs) of regional grey matter volume associated with performance on experimental tasks for the combined patient cohort, identified using voxel-based morphometry. Grey matter associations of semantic congruity processing in auditory scenes (left column), emotional congruity processing in auditory scenes (middle column) and auditory control tasks (right column) are presented (see text for details of contrasts). SPMs are overlaid on representative sections of the normalised study-specific T1-weighted mean brain MR image; the MNI coordinate (mm) of the plane of each section is indicated (the left cerebral hemisphere is shown on the left in the coronal sections and at the top in the axial section). Colour bars code T-score values for each SPM; SPMs are thresholded here at p < 0.001 uncorrected over the whole brain for display purposes, however regional local maxima were significant at p < 0.05FWE corrected for multiple voxel-wise comparisons within pre-specified anatomical regions of interest (see Table 3).