Table 1. Drugs from the FDA Table of Pharmacogenomic Biomarkers in Drug Labeling included in literature review.
| Therapeutic area | Count | Drugs |
|---|---|---|
| Oncology | 11 | Capecitabine, cisplatin, dabrafenib, fluorouracil, irinotecan, lapatinib, mercaptopurine, nilotinib, pazopanib, rasburicase, thioguanine |
| Infectious diseases | 10 | Abacavir, chloroquine, dapsone, mafenide, nalidixic acid, nitrofurantoin, primaquine, quinine sulphate, rifampin+isoniazid+pyrazinamidea, sulfamethoxazole+trimethoprima |
| Psychiatry | 9 | Aripiprazole, atomoxetine, citalopram, clozapine, fluvoxamine, iloperidone, perphenazine, pimozide, thioridazine |
| Neurology | 8 | Carbamazepine, clobazam, dextromethorphan+quinidinea, divalproex, phenytoin, tetrabenazine, valproic acid, vortioxetine |
| Cardiology | 5 | Carvedilol, clopidogrel, isosorbide+hydralazinea, metoprolol, propafenone |
| Gastroenterology | 5 | Dexlansoprazole, esomeprazole, metoclopramide, PEG-3350+sodium sulphate+sodium chloride+potassium chloride+sodium ascorbate+ascorbic acida, rabeprazole |
| Rheumatology | 5 | Azathioprine, carisoprodol, celecoxib, flurbiprofen, pegloticase |
| Endocrinology | 4 | Chlorpropamide, glimepiride, glipizide, glyburide |
| Haematology | 3 | Eltrombopag, methylene blue, warfarin |
| Analgesic | 1 | Tramadol |
| Anaesthesiology | 1 | Codeine |
| Dental | 1 | Cevimeline |
| Genitourinary | 1 | Tolterodine |
| Inborn errors of metabolism | 1 | Eliglustat |
| Pulmonary | 1 | Ivacaftor |
| Toxicology | 1 | Sodium nitrite |
| Transplantation | 1 | Mycophenolic acid |
Abbreviation: FDA, Food and Drug Administration.
Drugs in bold had economic evaluations available.
a
Multiple drugs on a single FDA label.