Table 1.
Study | Neutrophil count | Echo-based CFR (mean ± SE) | CFR increase | SD of PET-MPR [22] | Patients required (p < 0.05, 80% power) |
---|---|---|---|---|---|
Stable CAD cohort | |||||
5.8 | 2.10 ± 0.19 | 0.36 | |||
4.6 | 2.35 ± 0.12 | 10.6% | 0.36 | 33 | |
4.2 | 2.43 ± 0.11 | 13.5% | 0.36 | 19 | |
Post-MI cohort | |||||
5.8 | 2.45 ± 0.07 | 0.36 | |||
4.6 | 2.64 ± 0.05 | 7.2% | 0.36 | 57 | |
4.2 | 2.70 ± 0.05 | 9.3% | 0.36 | 33 |
Abbreviations: CFR Coronary flow reserve, PET Positron emission tomography, MPR Myocardial perfusion reserve, CAD Coronary artery disease, MI Myocardial infarction
The relationship between neutrophil count and echo-based CFR in both stable CAD and post-MI cohorts is shown. This demonstrates that lower neutrophil counts are associated with higher CFR