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. 2017 Mar 31;87(4):254–263. doi: 10.1159/000467393

Table 1.

Baseline characteristics

Total cohort
Subgroups by sex
Subgroups by puberty
n (n = 101) n female (n = 47) n male (n = 54) n prepubertal (n = 43) n pubertal (n = 57)
Age, years 101 10.9 (3.1) 47 10.3 (2.9) 54 11.4 (3.1) 43 8.4 (1.9) 57 12.8 (2.3)
BA, years 101 11.8 (2.1) 47 10.9 (2.9) 54 12.6 (2.9) 43 9.6 (2.0) 57 13.5 (2.5)
BA SDS 101 1.2 (1.1)* 47 0.8 (1.2)* 54 1.4 (1.0)* 43 1.6 (1.1)* 57 0.8 (1.1)*
Caucasiana 101 64 (63.4) 47 27 (57.4) 54 37 (68.5) 43 19 (44.2) 57 44 (77.2)
Height SDS 101 0.6 (1.0)* 47 0.4 (1.0)* 54 0.7 (1.1)* 43 0.8 (1.0)* 57 0.4 (1.0)*
BMI SDS 101 3.4 (0.6)* 47 3.1 (0.5)* 54 3.6 (0.7)* 43 3.6 (0.7)* 57 3.2 (0.5)*
Fasting insulin, mU/Lb 101 12 (6/18) 47 11 (6/19) 54 12 (7/16) 43 7 (4/11) 57 16 (10/26)
HOMA-IRb 101 2.1 (1.3/3.7) 47 2.1 (1.3/3.9) 54 2.3 (1.3/3.5) 43 1.3 (0.8/2.0) 57 2.4 (2.1/4.8)
AUC insulin, mU/Lb 94 305 (202/468) 43 267 (186/454) 51 309 (210/482) 40 211 (159/397) 53 362 (238/544)
Oestradiol SDS 50 0.0 (1.4) 21 −0.2 (1.1) 29 0.1 (1.5) 39 0.0 (1.3)
Testosterone SDSb 64 −0.6 (–1.2/0.3)* 28 −0.7 (–2.7/1.6) 36 −0.6 (–1.1/0.0)* 51 −0.7 (–1.3/0.4)*
DHEAS SDSb 96 0.4 (0.0/1.0)* 45 0.3 (–0.8/0.7) 51 0.4 (0.1/1.0)* 41 0.4 (–0.3/1.1) 54 0.3 (0.0/0.9)*
SHBG SDSb 96 −1.9 (–2.4/–1.1)* 46 −1.9 (–1.2/–2.2)* 50 −1.9 (–2.4/–1.1)* 40 −1.5 (–2.2/–0.7)* 55 −2.0 (–2.4/–1.4)*
Androstenedione, nmol/Lb 100 2.25 (1.30/3.60) 47 2.40 (1.20/4.10) 53 2.20 (1.30/3.30) 42 1.25 (0.78/2.23) 57 3.00 (2.15/4.50)

Data are expressed as mean (standard deviation) unless otherwise stated. Data on oestradiol SDS and testosterone SDS are on the age group of ≥9 years. SDS, standard deviation score; BA, bone age; BMI, body mass index; HOMA-IR, homeostatic model assessment of insulin resistance; AUC, area under the curve; DHEAS, dehydroepiandrosterone sulphate; SHBG, sex hormone-binding globulin.

a

n (%).

b

Median (interquartile range).

*

SDS, p < 0.05.