Table 4.
Backward regression analysis of BA SDS
| Coefficient | 95% CI | R2 | p value | |
|---|---|---|---|---|
| Total cohort (n = 88) | ||||
| Constant | 2.17 | 1.39/2.96 | <0.001 | |
| Male sex | 0.62 | 0.18/1.06 | 0.006 | |
| DHEAS SDS | 0.27 | 0.09/0.44 | <0.001 | |
| Age | −0.13 | −0.20/–0.06 | 0.036 | |
| Model | 0.27 | <0.001 | ||
| Female (n = 52) | ||||
| Constant | 2.68 | 1.25/4.11 | 0.001 | |
| DHEAS SDS | 0.34 | 0.01/0.66 | 0.042 | |
| SHBG SDS | 0.29 | −0.04/0.62 | 0.086 | |
| Age | −0.14 | −0.26/–0.02 | 0.024 | |
| Model | 0.21 | 0.030 | ||
| Male (n = 46) | ||||
| Constant | 2.81 | 1.80/3.81 | <0.001 | |
| DHEAS SDS | 0.31 | 0.09/0.52 | 0.006 | |
| Age | −0.14 | −0.22/–0.05 | 0.002 | |
| Model | 0.30 | <0.001 | ||
| Prepubertal (n = 36) | ||||
| Constant | 2.26 | 1.17/4.02 | 0.001 | |
| Male sex | 0.98 | 0.30/1.67 | 0.006 | |
| SHBG SDS | −0.41 | −0.76/–0.09 | 0.013 | |
| Age | −0.27 | −0.46/–0.07 | 0.009 | |
| Model | 0.31 | 0.006 | ||
| Pubertal (n = 37) | ||||
| Constant | 0.70 | 0.32/1.08 | 0.001 | |
| DHEAS SDS | 0.43 | 0.01/0.85 | 0.046 | |
| Model | 0.11 | 0.046 | ||
Variables included in all models: age, fasting insulin, HOMA-IR, AUC insulin, DHEAS SDS, SHBG SDS. In the total cohort and pubertal subgroups, sex was added as an independent variable. In the pubertal subgroup only, oestradiol SDS and testosterone SDS were added as independent variables. BA, bone age; HOMA-IR, homeostatic model assessment of insulin resistance; SHBG, sex hormone-binding globulin; DHEAS, dehydroepiandrosterone sulphate; SDS, standard deviation score.