Table 1.
Baseline characteristics of the study participants
| Lean | Obese | p | ISO | IRO | ANOVA |
Post hoc |
||||
|---|---|---|---|---|---|---|---|---|---|---|
| P | F | ISO vs. IRO | IRO vs. lean | ISO vs. lean | ||||||
| Number | 8 | 12 | 6 | 6 | ||||||
| M:F ratio | 0:8 | 2:10 | 1:5 | 1:5 | ||||||
| Age, years | 30.9 ± 10.5 | 31.3 ± 8.8 | 0.917 | 34.7 ± 9.9 | 28.0 ± 6.6 | 0.477 | 0.77 | |||
| BMI | 21.3 ± 1.3 | 36.6 ± 4.6 | <0.001 | 34.9 ± 3.8 | 38.3 ± 5.1 | <0.001 | 39.10 | 1 | <0.001 | <0.001 |
| Glucose, mmol/l | 4.4 ± 0.4 | 4.9 ± 0.4 | 0.008 | 4.8 ± 0.3 | 5.0 ± 0.4 | 0.019 | 5.04 | 0.882 | 0.019 | 0.206 |
| Insulin, pmol/l | 23 ± 13 | 106 ± 128 | 0.046 | 29 ± 11 | 184 ± 146 | 0.003 | 8.21 | 0.011 | 0.005 | 1 |
| C-peptide, mg/ml | 499 ± 102 | 873 ± 402 | 0.009 | 655 ± 83 | 1,092 ± 484 | 0.003 | 8.19 | 0.042 | 0.003 | 0.926 |
| Cortisol, nmol/l | 468 ± 242 | 342 ± 157 | 0.172 | 271 ± 85 | 412 ± 188 | 0.185 | 1.87 | |||
| Glucagon, ng/l | 73 ± 20 | 94 ± 31 | 0.114 | 95 ± 36 | 92 ± 28 | 0.291 | 1.33 | |||
| HOMA-IR | 0.7 ± 0.5 | 3.4 ± 4.2 | 0.045 | 0.9 ± 0.3 | 6.0 ± 4.8 | 0.003 | 8.36 | 0.011 | 0.005 | 1 |
Data are presented as mean ± SD.