Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Compartmental pharmacokinetic model for MOD-4023 (left) and indirect pharmacodynamic model for IGF-1 (right). In the pharmacokinetic model, MOD-4023 is administered subcutaneously and absorbed into the central compartment, then distributed to the peripheral compartment. In the pharmacodynamic model, the serum concentration of MOD-4023 affects the input the IGF-1 into the serum compartment; elimination of IGF-1 is a first-order process not affected by MOD-4023. SC, subcutaneous.
