Table 1.
Per-HLA gene imputation accuracy in imputing HLA information on 61 HapMap CHB+JPT samples
| HLA gene | A | B | C | DRB1 | DPB1 | DQB1 | Average |
|---|---|---|---|---|---|---|---|
| Pan-Asian | 0.893 | 0.721 | 0.893 | 0.852 | 0.926 | 0.909 | 0.866 |
| (0.838−0.948) | (0.641−0.801) | (0.891−0.895) | (0.838−0.948) | (0.880−0.972) | (0.858−0.960) | (0.841−0.891) | |
| Korean | 0.901 | 0.893 | 0.983 | 0.893 | 0.926 | 0.893 | 0.915 |
| (0.848−0.954) | (0.838−0.948) | (0.960−1.001) | (0.838−0.948) | (0.876−0.972) | (0.838−0.948) | (0.895−0.935) | |
| Merged panel | 0.943 | 0.910 | 0.992 | 0.951 | 0.926 | 0.910 | 0.939 |
| (0.902−0.984) | (0.859−0.961) | (0.976−1.001) | (0.913−0.990) | (0.876−0.972) | (0.859−0.961) | (0.922−0.956) |
The accuracies and 95% confidence intervals were based on 4-digit imputation using SNP2HLA.
HLA, human leukocyte antigen; CHB, Beijing, China; JPT, Tokyo, Japan.