Case study of one CAMEO target 5h35E. (A) The long- and medium-range contact prediction accuracy of our methods, MetaPSICOV, CCMpred, and EVfold (web server). (B–D) The overlap between the native contact map and contact maps predicted by our method, CCMpred, MetaPSICOV, and EVfold. Top L predicted all-range contacts are displayed. A grey, red and green dot represents a native contact, a correct prediction and a wrong prediction, respectively. (E) The superimposition between our predicted model (in red) and the native structure (in green).