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. Author manuscript; available in PMC: 2018 Sep 15.
Published in final edited form as: Org Lett. 2017 Aug 29;19(18):4876–4879. doi: 10.1021/acs.orglett.7b02336

Scheme 1.

Scheme 1

Ruthenium catalyzed C-C coupling of alcohols 2a–2u with acetylenic pyrrole 1 to form products of carbonyl anti-(α-amino)allylation 3a–3u.a

aYields are of material isolated by silica gel chromatography. b2-PrOH (200 mol %). c48h. ddioxane (1 M). See Supporting Information for further experimental details.