Table 3.
Demographic, clinical and laboratory profile of dengue and nondengue patients, Nepal
| Variable | Dengue (N = 128) | Nondengue (N = 154) | Total (N = 282) | P value |
|---|---|---|---|---|
| Demographic | ||||
| Age in years, median (IQR) | 29.5 (21.3–40.0) | 26.0 (17.0–40.0) | 28.0 (19.0–40.0) | 0.004 |
| Residence, urban | 93 (72.7) | 65 (42.2) | 158 (56.0) | < 0.001 |
| Prior visit to clinics/pharmacy | 58 (45.3) | 67 (43.5) | 125 (44.3) | 0.761 |
| Clinical | ||||
| DOI, median (IQR) | 4.5 (3.0–7.0) | 4.0 (2.0–7.0) | 4.0 (2.8–7.0) | 0.503 |
| Fever | 128 (100.0) | 154 (100.0) | 282 (100.0) | – |
| Headache | 118 (92.2) | 134 (87.0) | 252 (89.4) | 0.161 |
| Nausea | 91 (71.1) | 97 (63.0) | 188 (66.7) | 0.150 |
| Vomiting | 46 (35.9) | 37 (24.0) | 83 (29.4) | 0.029 |
| Rash | 48 (37.5) | 21 (13.6) | 69 (24.5) | < 0.001 |
| Myalgia | 44 (34.4) | 52 (33.8) | 96 (34.0) | 0.914 |
| Bleeding | 18 (14.1) | 4 (2.6) | 22 (7.8) | < 0.001 |
| Retro-orbital pain | 56 (43.8) | 39 (25.3) | 95 (33.7) | 0.001 |
| Diarrhea | 29 (22.7) | 25 (16.2) | 54 (19.1) | 0.172 |
| Sore throat | 9 (7.0) | 22 (14.3) | 31 (11.0) | 0.053 |
| Chills | 12 (9.4) | 37 (24.0) | 49 (17.4) | 0.001 |
| Abdominal pain | 36 (28.1) | 49 (31.8) | 85 (30.1) | 0.501 |
| Arthralgia | 19 (14.8) | 17 (11.0) | 36 (12.8) | 0.340 |
| Hepatomegaly | 43 (33.6) | 35 (22.7) | 78 (27.7) | 0.042 |
| Splenomegaly | 17 (13.3) | 11 (7.1) | 28 (9.9) | 0.086 |
| Laboratory | ||||
| Elevated AST (> 50 IU/L) | 81 (63.3) | 44 (28.6) | 125 (44.3) | < 0.001 |
| Elevated ALT (> 50 IU/L) | 57 (44.5) | 28 (18.2) | 85 (30.1) | < 0.001 |
| Thrombocytopenia | 75 (58.6) | 35 (22.7) | 110 (39.0) | < 0.001 |
| Leucopenia | 55 (43.0) | 40 (26.0) | 95 (33.7) | 0.003 |
AST = serum aspartate aminotransferase; ALT = serum alanine aminotransferase; DOI = days postonset of illness; IQR = interquartile range; IU/L = international unit/liter. Figures in the parenthesis indicate percentages unless otherwise indicated. P value was calculated using Mann–Whitney U test for age and DOI, and χ2 test for all categorical variables.