Table 2.
Cure rates of PZQ 40 mg/kg stratified by demographic characteristics and baseline infection intensity.
| Characteristic | Treatment regimen | ||||
|---|---|---|---|---|---|
| Single dose | Double dose | p value | |||
| Treated (N) | Cured n (%(95% CI)) | Treated (N) | Cured n (%(95% CI)) | ||
| Overall | 182 | 125 (68.68 (61.90–75.46)) | 174 | 162 (93.10 (89.31–96.89)) | <0.001 |
| Sex | |||||
| Male | 89 | 66 (74.16 (64.94–83.69)) | 81 | 78 (96.30 (92.13–100)) | <0.001 |
| Female | 93 | 59 (63.44 (53.54–73.35)) | 93 | 84 (90.32 (84.24–96.40)) | <0.001 |
| Village | |||||
| Kibuyi | 96 | 61 (63.54 (53.80–73.28)) | 85 | 82 (96.47 (92.49–100)) | <0.001 |
| Busanga | 86 | 64 (74.42 (65.08–83.76)) | 89 | 80 (89.89 (83.54–96.23)) | 0.007 |
| Age (years) | |||||
| 6–9 | 38 | 19 (50.00 (33.63–66.37)) | 39 | 38 (97.44 (92.33–100)) | <0.001 |
| 10–12 | 84 | 60 (71.43 (61.64–81.22)) | 87 | 81 (93.10 (87.71–98.49)) | <0.001 |
| 13–16 | 60 | 46 (76.67 (65.75–87.58)) | 48 | 43 (89.58 (80.75–98.41)) | 0.080 |
| Intensity | |||||
| Light | 64 | 47 (73.44 (62.41–84.46)) | 49 | 46 (93.88 (87.02–100)) | 0.005 |
| Moderate | 86 | 57 (66.28 (56.15–76.41)) | 66 | 63 (95.45 (90.35–100)) | <0.001 |
| Heavy | 32 | 21 (65.63 (48.68–82.57)) | 59 | 53 (89.83 (81.95–97.72)) | 0.005 |
p values are based on chi-square statistic.