Table 5.
Summary of reported miRNAs and their targets in Inflammatory Response.
| miRNAs | Targets | Regulation factors | References |
|---|---|---|---|
| MiR-155 | SOCS1, SHIP1, IL-13Ra1 | IFN-b, TNF-a, IL-1 | [141–146] |
| miR-125a | TNFAIP3 (A20) | LPS | [147] |
| miR-125b | TNFAIP3, TNF-a | LPS | [123, 147] |
| miR-125a-5p | TLR2, TLR4 | LPS | [148] |
| miR-21 | CSF-1R | LPS | [149] |
| miR-22 | Rasa1, Nfat5 | PPARg | [150] |
| miR-27a | PPARg | M-CSF | [151] |
| Mir-375 | PDK1 | M-CSF | [152] |
| MiR-126 | ADAM9 | LPS | [153] |
| MiR-145-5p | CD40 | IL-1β, TNF-α, IL-6 | [154] |
| MiR-146a | IRAK, TRAF6 | LPS, TNF-α | [155] |
SOCS1: suppressor of cytokine signaling 1; SHIP1: inositol polyphosphate-5-phosphatase D; TNF-a: tumor necrosis factor a; LPS: lipopolysaccharides; CSF-1R: colony stimulating factor 1 receptor; Rasa1: RAS p21 protein activator 1; Nfat5: nuclear factor of activated T-cells 5; PDK1: pyruvate dehydrogenase kinase 1; IRAK: interleukin 1 receptor associated kinase; TRAF6: TNF receptor associated factor 6; ADAM9: A disintegrin and metalloproteinase 9.