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. 2017 Apr 5;11(9):1124–1134. doi: 10.1093/ecco-jcc/jjx050

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© European Crohn’s and Colitis Organisation 2017.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — CCR expression profile of systemic T cells differs between patients with PSC-UC, UC patients, and controls. [A] Representative gating strategy. Cells were gated on lymphocytes, CD3⁺, CD45RO⁺CD45RA^- memory, CD4⁺ T cells. β7, CCR9, CCR4, CCR6, CCR10, and CXCR3 staining and FMO controls are shown. [B] Frequency of positive cells among CD45RO⁺CD4⁺ cells in patients with PSC-UC, UC, and controls. †P < 0.05, ††P < 0.01, †††P < 0.001, Mann-Whitney test vs controls. CCR, chemokine receptor; PSC-UC, primary sclerosing cholangitis-ulcerative colitis.