Table 1.
Details of post mortem samples
| Sample # | Study group | Age (years) | Used in proteomic analysis | Braak stage | Thal amyloid phase | Post mortem delay (h) | Cause of death | Duration of dementia (years) | CAA inflammation/vasculitis |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Young control | 51 | Yes | 0 | Not applicable | 81 | Metastatic carcinoma | 0 | Not applicable |
| 2 | Young control | 46 | Yes | 0 | Not applicable | 49 | Myocardial infarction; coronary artery thrombosis; coronary artery atherosclerosis | 0 | Not applicable |
| 3 | Young control | 45 | No | 0 | Not applicable | 93 | Coronary artery atherosclerosis | 0 | Not applicable |
| 4 | Young control | 40 | No | 0 | Not applicable | 77 | Bronchial asthma | 0 | Not applicable |
| 5 | Young control | 45 | No | 0 | Not applicable | 40 | Suspension by ligature | 0 | Not applicable |
| 6 | Elderly control | 79 | Yes | IV | 3 | 9 | Old age, dementia with Parkinson's disease | 9 | Mild, some vessels with perivascular infiltrate |
| 7 | Elderly control | 88 | Yes | III | 0 | 22 | Aspiration pneumonia; total anterior circulation stroke | Not available | Not remarkable |
| 8 | Elderly control | 74 | No | III | 1 | 53 | Heart failure and lung cancer | Not available | Not remarkable |
| 9 | Elderly control | 94 | No | II | 1 | 15 | Left ventricle failure; ischaemic heart disease | Not available | Not remarkable |
| 10 | Elderly control | 95 | No | III | 0 | 66 | Ischaemic bowel disease (inoperable) | Not available | Not remarkable |
| 11 | Elderly control | 96 | No | II | 3 | 114 | Stroke and left ventricular failure | 2 (mild) | Not remarkable |
| 12 | Elderly control | 92 | No | VI | 5 | 74 | Pneumonia | >2 | Not remarkable |
| 13 | CAA case | 93 | Yes | VI | 5 | 53 | Stroke, general deterioration | 13 | Mild, some vessels with perivascular infiltrate |
| 14 | CAA case | 73 | Yes | IV | 5 | 47 | Frontal lobe dementia | 1.3 | Not remarkable |
| 15 | CAA case | 76 | Yes | VI | 3 | 37 | not applicable | 8 | Not remarkable |
| 16 | CAA case | 87 | Yes | VI | 5 | 54 | Aspiration pneumonia secondary to stroke | 8 | Not remarkable |
| 17 | CAA case | 86 | No | VI | 5 | 47 | not applicable | 6 | Not remarkable |
| 18 | CAA case | 77 | No | VI | 2 | 63 | Aspiration pneumonia | 14 | Not remarkable |
| 19 | CAA case | 88 | No | VI | 5 | 84 | Bronchopneumonia | 15 | Not remarkable |
CAA, cerebral amyloid angiopathy.