Table 4. Age-adjusted death rates by baseline variable by anti-CCP and DMARD use in self-reported RA, excluding history of RA at follow up only (weighted).
| Age-adjusted Death Rates/1000 PYs | |||||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| Baseline Measurement | Weighted Total | Anti-CCP+ (N=812) | Weighted total | Anti-CCP- /DMARD use at baseline (N=217) | Weighted total | Anti-CCP-/No DMARD use at baseline (N=8951) | Never self-reported RA (N=122,275) |
| Age | |||||||
| 50-59 | 262 | 9.2 (6.3-13.5) | 74 | 4.9 (1.9-12.8) | 1894 | 5.3 (4.4-6.3) | 3.2 (3.1-3.3) |
| 60-69 | 313 | 17.8 (13.8-22.9) | 102 | 16.0 (10.2-25.3) | 2617 | 10.6 (9.5-11.8) | 7.4 (7.2-7.6) |
| 70-79 | 178 | 43.8 (34.9-55.1) | 69 | 32.7 (21.7-49.3) | 1713 | 24.7 (22.5-27.1) | 17.6 (17.1-18.1) |
|
| |||||||
| Ethnicity | |||||||
| Black | 149 | 12.1 (6.4-23.3) | 31 | 17.6 (6.1-52.5) | 979 | 11.5 (9.3-14.3) | 10.8 (9.8-12.0) |
| Hispanic | 41 | 22.6 (8.5-62.8) | 4 | 0 | 322 | 7.3 (4.6-11.4) | 7.1 (5.8-8.8) |
| White | 563 | 20.3 (15.8-26.1) | 210 | 18.3 (11.4-29.7) | 4928 | 9.9 (9.1-10.9) | 8.6 (8.3-8.9) |
|
| |||||||
| Education | |||||||
| ≤High school | 194 | 24.2 (16.0-37.1) | 58 | 13.3 (4.8-39.7) | 1752 | 10.2 (8.7-11.9) | 9.7 (9.1-10.3) |
| Some college | 306 | 16.3 (11.1-23.9) | 94 | 25.3 (13.9-47.1) | 2486 | 10.5 (9.2-11.9) | 9.0 (8.6-9.5) |
| ≥College | 243 | 17.0 (11.4-25.7) | 92 | 14.0 (6.1-32.5) | 1929 | 9.52 (8.2-11.1) | 7.9 (7.6-8.3) |
|
| |||||||
| Smoking | |||||||
| Never | 303 | 14.9 (10.1-22.4) | 105 | 15.7 (7.7-32.6) | 3120 | 8.7 (7.7-9.9) | 6.9 (6.6-7.3) |
| Past | 360 | 18.7 (13.5-26.0) | 121 | 20.9 (11.6-38.3) | 2506 | 10.2 (8.9-11.6) | 9.5 (9.1-9.9) |
| Current | 81 | 27.8 (15.4-50.5) | 18 | 0 | 491 | 20.0 (15.6-25.6) | 19.3 (17.7-21.1) |
|
| |||||||
| General health | |||||||
| Excellent/very good | 191 | 12.1 (7.7-19.6) | 89 | 7.3 (6.3-8.5) | 2521 | 7.3 (6.3-8.5) | 6.7 (6.4-7.0) |
| Good | 350 | 18.3 (13.0-26.1) | 124 | 10.1 (8.9-11.6) | 2477 | 10.1 (8.9-11.6) | 10.2 (9.7-10.7) |
| Fair/poor | 205 | 29.9 (20.1-44.6) | 31 | 17.5 (14.9-20.5) | 1190 | 17.5 (14.9-20.5) | 19.0 (17.6-20.5) |
|
| |||||||
| Diabetes | |||||||
| No | 712 | 17.8 (14.0) | 219 | 9.1 (8.3-10.0) | 5623 | 9.1 (8.3-10.0) | 8.1 (7.9-8.4) |
| Yes | 41 | 32.3 (16.1-66.7) | 25 | 21.4 (17.4-26.4) | 600 | 21.4 (17.4-26.4) | 18.9 (17.3-20.6) |
|
| |||||||
| CHD at baseline | |||||||
| No | 687 | 17.5 (13.7-22.5) | 224 | 8.9 (8.1-9.8) | 5329 | 8.9 (8.1-9.8) | 8.2 (7.9-8.4) |
| Yes | 66 | 33.3 (18.0-63.2) | 21 | 19.2 (16.0-23.3) | 900 | 19.2 (16.0-23.3) | 15.9 (14.6-17.4) |
|
| |||||||
| Physical function construct (SF36) | |||||||
| ≤ 85 | 589 | 20.2 (15.6-26.2) | 208 | 12.1 (11.0-13.3) | 4143 | 12.1 (11.0-13.3) | 11.0 (10.6-11.4) |
| >85 | 134 | 13.6 (7.7-24.1) | 35 | 6.4 (5.3-7.6) | 1939 | 6.4 (5.3-7.6) | 6.2 (5.9-6.6) |
|
| |||||||
| Waist circumference (cm) | |||||||
| ≤88 | 460 | 16.3 (12.0-22.4) | 134 | 8.7 (7.7-9.8) | 3113 | 8.7 (7.7-9.8) | 7.6 (7.3-7.9) |
| >88 | 291 | 22.6 (16.2-31.6) | 108 | 11.5 (10.2-12.8) | 3092 | 11.5 (10.2-12.8) | 10.5 (10.0-10.9) |
|
| |||||||
| Total METs per week | |||||||
| <2.5 | 264 | 22.9 (15.7-33.4) | 89 | 13.6 (11.9-15.7) | 1847 | 13.6 (11.9-15.7) | 11.0 (10.4-11.6) |
| 2.5-18.4 | 359 | 18.6 (13.3-26.3) | 124 | 9.4 (8.3-10.7) | 3040 | 9.4 (8.3-10.7) | 8.5 (8.1-8.8) |
| ≥18.25 | 129 | 13.4 (7.7-24.6) | 31 | 7.4 (6.0-9.1) | 1326 | 7.4 (6.0-9.1) | 7.0 (6.6-7.5) |
|
| |||||||
| Hypertension | |||||||
| No | 479 | 18.3 (13.7-24.5) | 146 | 7.7 (6.8-8.8) | 3490 | 7.7 (6.8-8.8) | 7.3 (7.0-7.6) |
| Yes | 270 | 20.1 (13.9-29.1) | 96 | 13.3 (11.8-14.9) | 2678 | 13.3 (11.9-14.9) | 11.3 (10.8-11.8) |