Figure 5.
High P2-HNF4α expression is associated with unfavourable outcomes in subgroups of HCC patients. Stratified survival analyses show that P2- HNF4α expression is correlated with overall survival in small and large HCCs (a) in single and multinodular HCC (b), in HCCs with normal and abnormal AFP levels (c), in HBsAg positive and negative HCCs (d), in HCCs with or without microvascular invasion (e), and in HCCs with well-moderate differentiation and poor-undifferentiated differentiation (f).
HBsAg, hepatitis B surface antigen; HCC, hepatocellular carcinoma; HNF4α, hepatocyte nuclear factor 4 alpha; P1, promoter 1; P2, promoter 2.