Table 1.

Association of P2-HNF4α expression and clinical features in hepatocellular carcinoma.

Variable	P2-HNF4α		p-value
	Low expression	High expression
Sample size	456	159
Age, years	48.76 ± 12.21	49.49 ± 11.76	0.507
Sex			0.815
Male	413	145
Female	43	14
HBsAg			0.741
Positive	388	137
Negative	68	22
AFP, ng/ml			0.081
<20	133	35
⩾20	323	124
Cirrhosis			0.942
Yes	374	130
No	82	29
Tumour size, cm			0.299
<5	102	42
⩾5	354	117
Tumour multiplicity			0.206
Single	270	85
Multiple	186	74
Differentiation			0.048
Well-moderate	309	94
Poor-undifferentiated	147	65
TNM stage			0.083
I–II	240	71
III–IV	216	88
Vascular invasion			0.017
Yes	78	41
No	378	118
Involucrum			0.663
Complete	275	99
Incomplete	181	60

AFP: α-fetoprotein; HBsAg: hepatitis B virus surface antigen; HNF4α, hepatocyte nuclear factor 4 alpha; P2, promoter 2.