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. 2017 Oct 12;12(10):e0185879. doi: 10.1371/journal.pone.0185879

Table 2. Changes in inflammatory parameters from baseline to 12 weeks.

Differences
over timea
Differences
between groupsb
Mean change (95% CI) p-value p-value
TNF-α (pg/ml) PTN −0.32 (−1.24–0.38) 0.287 0.469
SoSu −0.47 (−1.40–0.46) 0.303
Log-IL-6 (pg/ml) PTN 0.11 (−0.11–0.33) 0.304 0.343
SoSu 0.19 (0.00–0.37) 0.047
Log-CRP (mg/dl) PTN 0.08 (−0.16–0.32) 0.501 0.040
SoSu 0.46 (0.07–0.85) 0.022
Leukocytes total (g/l) PTN 0.48 (−0.04–1.01) 0.070 0.839
SoSu 0.46 (−0.22–1.13) 0.177

PTN = physical training and nutritional intervention group (n = 35); SoSu = social support group (n = 23).

a Differences over time were calculated using paired t-tests. Mean change and 95% confidence interval (95% CI) are presented.

b Differences between groups were calculated using analysis of covariance (ANCOVA) for repeated measurements, adjusted for baseline value, sex, age, anti-inflammatory medication, and chronic rheumatism.