Skip to main content
. 2017 Oct 12;12(10):e0186244. doi: 10.1371/journal.pone.0186244

Fig 1. Schematic diagram of adenovirus (Ad) vector constructs used in the study.

Fig 1

(A) Ad-ΔE1E3; human adenovirus type C5 (Ad-C5) empty vector. (B) Ad-H5HA, Ad-H7HA and Ad-H9HA; Ad-C5 vector containing a full-length coding region of H5 hemagglutinin (HA) of A/Vietnam/1203/04(H5N1), H7 HA of A/Netherlands/219/2003(H7N7) or H9 HA of A/chicken/Hong Kong/G9/1997(H9N2), respectively. (C) Ad-H5ME, Ad-C5 vector containing multi-epitope (ME) gene construct of A/Vietnam/1203/ 2004(H5N1) that contains the extracellular domain of M2 (M2e), fusion domain of HA (HFD), T-cell epitope of nucleoprotein [NP] (TNP), and alpha helix domain of HA (HαD).