Table 1. Summary of patient characteristics.
Patient code | CD4 cell count (cells/μl)* | Plasma HIV-1 RNA level (copies/ml)* | Documented PHI | Fiebig stage* | BED ODn* | Days last neg.-first pos.** | Estimated “true” time of infection (TI) | TI method | No. of samples | Days between TI and first sequence | Years between TI and last sequence |
---|---|---|---|---|---|---|---|---|---|---|---|
p1 | 537 | <500 | No | VI | 0.419 | 310 | 7/9/1996 | BED + Fiebig VI | 12 | 122 | 8.2 |
p2 | 1185 | 31100 | No | V | 0.171 | 397 | 7/28/2002 | Fiebig V | 6 | 74 | 5.5 |
p3 | 694 | 17300 | No | VI | 0.898 | 575 | 9/3/1999 | BED | 10 | 146 | 8.4 |
p4 | 1064 | 6780 | No | V | 0.170 | 620 | 10/2/2000 | Fiebig V | 8 | 93 | 8.4 |
p5 | 521 | <50 | No | VI | 0.153 | 196 | 12/10/2002 | BED + Fiebig VI | 7 | 134 | 5.9 |
p6 | 480 | 6800 | Yes | IV | 0.290 | 45 | 9/25/2002 | PHI | 7 | 62 | 7.0 |
p7 | 496 | 497 | No | VI | nd | 190 | 6/18/1990 | Midpoint | 10*** | 2248 | 15.9 |
p8 | 460 | 2900 | No | V | 0.158 | 299 | 4/19/1998 | Fiebig V | 7 | 87 | 6.0 |
p9 | 720 | 2300 | No | VI | 0.277 | 614 | 11/24/1996 | BED + Fiebig VI | 8 | 106 | 8.1 |
p10 | 420 | 594000 | Yes | II | 0.101 | 16 | 5/19/1990 | PHI | 9 | 33 | 6.2 |
p11 | 850 | 12700 | No | VI | 1.222 | 642 | 9/22/2000 | BED | 7 | 208 | 5.6 |
Table notes: PHI, primary HIV-1 infection; BED ODn, normalized optical density level in the BED serological assay; TI, estimated “true” date of infection;
*Results at baseline;
**Days between last negative and first positive HIV-1 test;
*** Sequencing of earlier time points failed due to low virus levels.