FIGURE 1:
PLCγ1 is required for EGF but not Tfn internalization. RPE cells were treated with siRNA targeting PLCγ1 or nontargeting siRNA, followed by measurement of EGF (A), Tfn (B), or Tfn internalization in EGF-stimulated cells (C). Shown are the means ± SE for n > 3 independent experiments; *, p < 0.05.