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. 2017 Oct 15;28(21):2802–2818. doi: 10.1091/mbc.E16-12-0871

FIGURE 4:

FIGURE 4:

PKC, but not calcineurin, is selectively required for EGF internalization. RPE cells were treated with 10 μM CsA for 30 min or 1 μM BIM for 30 min, or left untreated (control), followed by measurement of EGF (A, B), Tfn (C), or Tfn internalization in EGF-stimulated cells (D). Shown are the means ± SE for n > 3 independent experiments; *, p < 0.05.