FIGURE 4:
PKC, but not calcineurin, is selectively required for EGF internalization. RPE cells were treated with 10 μM CsA for 30 min or 1 μM BIM for 30 min, or left untreated (control), followed by measurement of EGF (A, B), Tfn (C), or Tfn internalization in EGF-stimulated cells (D). Shown are the means ± SE for n > 3 independent experiments; *, p < 0.05.